Chapter 7 Poaching
At the same time, in Ji Hong's office.
Ji Hong was sitting in front of the computer at the moment, frowning as he asked questions.
As a teacher majoring in pharmacy, he naturally writes the students' final exam papers.
Lao Ji, if your questions are so difficult, I'm afraid many students will fail!
At this moment, a teacher standing next to Ji Hong holding a thermos cup said with a smile.
Ji Hong frowned and sighed: Teacher Zhou, to be honest, if students still fail the exam because of a question of this level, then I can't be blamed.
These are all things that were taught in class, and I even highlighted the key points for them before the exam.
Zhou Feng shook his head: Old Ji, it's not like you don't know today's students. Except for a few students who attend classes, other students are either sleeping or playing on their mobile phones during class.
It's just a quick review before the exam, just to make ends meet.
When Zhou Feng said this, Ji Hong couldn't help but rub his swollen eyebrows.
At this moment, there was a sudden knock on the office door.
Ji Hong put down the tea cup in his hand: Who is it?
The door of the office was pushed open, and a student wearing glasses walked in: Teacher, the cell experiment you requested has been completed, and I have sent the data.
So fast?
Ji Hong was slightly surprised.
The student nodded: My senior brother and I did this together.
Ji Hong nodded: You have worked hard these past few days, you should take a rest first.
After his student left, Ji Hong opened the chat software and found the experimental data sent to him by the student.
This experimental data was exactly the experimental data of the second-generation drug that Lu Liang gave him.
After obtaining the second-generation drug synthesis route, Ji Hong had the entire research team start working overtime to start testing.
The raw materials needed to synthesize drugs are available in the laboratory.
Therefore, the synthesis of drugs is not a big problem for Ji Hong.
The most important thing is the next cell test. In order to prevent unexpected situations, Ji Hong specially conducted three batches of cell tests.
The entire team can be said to be operating 24 hours a day.
Finally, the results of the cell test came out today.
Zhou Feng said with a smile: Old Ji, as expected of you, have you found a new research direction?
Ji Hong shook his head: It's not me, it's one of my students who said he had screened out a second-generation treatment drug for chronic myelogenous leukemia. I'll help him verify it.
Zhou Feng immediately became interested when he heard this: Then you are a great student. Are you the one who brought out the two Ph.D.'s?
Ji Hong still shook his head.
Zhou Feng was a little surprised: It's not a doctor. Is it the masters you brought with you? Have their research on drugs reached this level?
Ji Hong still shook his head.
This made Zhou Feng suddenly puzzled: I'm not a doctor or a master. Lao Ji, do you have other students with you?
Ji Hong sighed: This drug was selected by a freshman undergraduate student I taught.
Zhou Feng was stunned for a moment. When he came to his senses, his face was full of disbelief: Undergraduate student, or freshman?
Ji Hong nodded: I have been studying with me since I entered school, and it has been almost a year now.
Zhou Feng was a little unbelievable: No, Lao Ji, your student is not making it up, is he? What kind of drug molecules can an undergraduate screen out?
Ji Hong understood why Zhou Feng said this, because just from the sound of it, it felt unreliable.
If Ji Hong hadn't seen the incredibly detailed drug synthesis route, he wouldn't have believed what Lu Liang said.
Ji Hong said: Let's take a look at the test results first.
As Ji Hong spoke, he skillfully threw the test data into SPSS for analysis and calculation.
Zhou Feng also nodded, and his eyes moved from Ji Hong to the computer screen.
The test data results came out quickly. However, when they saw the results of the first batch of test data, Ji Hong and Zhou Feng were stunned.
P\u003c0.01, proving that the second-generation drug is effective.
Zhou Feng came to his senses first and said with a smile: Is it a coincidence?
Ji Hong thought for a while and felt that the possibility of coincidence was very high, and experiments were sometimes affected by various factors.
Ji Hong also threw the second batch of data into SPSS for calculation.
After seeing the second batch of data results, Ji Hong and Zhou Feng could not help but frown, and their expressions were slightly solemn.
Because the results of the second batch of trials are still the same.
Ji Hong then sent the third batch of data. The moment he pressed the confirm button, the data was immediately analyzed.
After reading the results of the three batches of experimental data, Ji Hong subconsciously leaned back slightly.
At this moment, Zhou Feng's eyes widened even more, and he murmured in a low voice: Real or false?
And judging from the results of the data.
Compared with the control group, the degree of p210 protein and its substrate tyrosine phosphorylation in the cells of the three batches of experimental groups were extremely significantly inhibited.
What does this mean?
This shows that second-generation drugs really have a therapeutic effect on chronic myelogenous leukemia!
If we say before, Ji Hong was only hesitant about the second-generation drug dasatinib being able to treat chronic myelogenous leukemia.
And now, when all the experimental data is placed in front of him.
No matter how much Ji Hong didn't believe it, he had to admit that what Lu Liang said was true and he was not talking nonsense.
In addition to the accident, Ji Hong felt more shocked.
You know, how many scientific researchers spend their entire lives not being able to guarantee that they can screen out an effective compound.
But now Lu Liang has done it. The key is that Lu Liang is still only a freshman.
Most freshman students have not yet understood the professional courses at this time.
Not only Ji Hong, but Zhou Feng on the side was also dumbfounded.
His expression changed from disdain at the beginning to hesitation and silence at the end. With each result, the expression on his face changed again and again.
After coming back to his senses, Zhou Feng looked at Ji Hong in surprise: Old Ji, did you just say that this was caused by a freshman you led?
Ji Hong nodded.
Zhou Feng thought for a moment: What's the name of your student?
he is.
Ji Hong seemed to realize something. He suddenly looked at Zhou Feng warily: Hey, Lao Zhou, what do you want to do, poach?
Zhou Feng, whose purpose was exposed, coughed dryly: What do you mean by poaching, Lao Ji, don't say it in such a bad way. He is not in graduate school yet. What if he has other ideas in the future?
Go, go, go, how could my students have other ideas.
After hearing this, Ji Hong suddenly became unhappy.
Hey, Lao Ji, at least tell me the student's name first.
In the end, Zhou Feng was kicked out by Ji Hong as expected, but Zhou Feng also learned Lu Liang's name from Ji Hong's mouth.
After driving Zhou Feng out, the office became quiet.
Ji Hong looked at the results on the computer screen. He had now calmed down from his excitement.
The success of the cell experiment does not mean that the matter is over. On the contrary, this is the real beginning.
Because, what comes next is the most important thing.
Phase III clinical trials of the drug!
He has studied in the field of innovative drugs for so many years and has seen countless drugs that are effective in cell experiments and animal experiments.
But after entering clinical trials, the results became a mess.
Only drugs that can pass Phase III clinical testing are truly drugs that can be used!
After Ji Hong thought for a moment, he picked up his cell phone and made a call: Hey, Lao He, are you free recently?
Yes, yes, I have a new drug here that needs to be tested for pharmacokinetics and toxicology.
How soon can the results report be issued?
Okay, I'll send you the drug sample as soon as possible, and I'll leave you with the testing.
Dean Chen, it's me, Ji Hong.
I would like to ask your hospital to conduct a phase III clinical trial of chronic myelogenous leukemia drugs.
How long will it take to get the results?
Really? That's really troublesome for you, Dean Chen.
After making several phone calls in a row, Ji Hong breathed a sigh of relief.
Now that all the problems have been solved, only two test reports on pharmacokinetics and pharmacotoxicology can be issued, and the drug can begin clinical trials.
Whether Lu Liang's second-generation drug can be successful depends on the next phase three clinical trials.